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Vitamin C induces HSP expression and reduces lipid peroxidation, though high-dose use ( 5 g/day) carries a risk of renal stone formation [81]

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After being blocked with 10% normal goat serum for 1 h at room temperature, the slides were subsequently incubated overnight with IL-4, TNF-, p-p38, ERK1, ERK2, RIP1, RIP3, and MLKL

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The findings were groundbreaking: at the 6-month mark, subjects taking the 1,000 mg daily dose experienced a 30% to 35% increase in glutathione levels within their erythrocytes (red blood cells), plasma, and lymphocytes